Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593105 | 1.00 | CAPN1 (0.53) | CAPN1CAPN2CTSKS1PR4S1PR1 | |
| SCHEMBL28270213 | 0.89 | PSMB5 (0.58) | CAPN1CAPN2CTSKS1PR4S1PR1 | |
| SCHEMBL28270212 | 0.89 | PSMB5 (0.58) | CAPN1CAPN2CTSKS1PR4S1PR1 | |
| SCHEMBL9830988 | 0.87 | MMP1 (0.56) | CAPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL18775036 | 0.82 | CTSK (0.57) | CTSKS1PR4S1PR1CTSSCTSL | |
| SCHEMBL18791070 | 0.82 | CTSK (0.57) | CTSKS1PR4S1PR1CTSSCTSL | |
| SCHEMBL621466 | 0.82 | IL1RN (0.53) | CTSKCTSB | |
| SCHEMBL621467 | 0.82 | IL1RN (0.53) | CTSKCTSB | |
| SCHEMBL9832022 | 0.82 | POLB (0.56) | CAPN1ACE | |
| SCHEMBL3394165 | 0.81 | CTSK (0.56) | CTSKS1PR4S1PR1CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |