Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832022 | 0.90 | POLB (0.56) | CAPN1 | |
| SCHEMBL7357746 | 0.87 | CAPN1 (0.53) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL10593105 | 0.87 | CAPN1 (0.53) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL9830801 | 0.85 | NPY5R (0.54) | MMP1 | |
| SCHEMBL28602197 | 0.82 | CTSK (0.72) | MMP1CTSKCTSLCTSSCTSB | |
| SCHEMBL15251947 | 0.81 | ALDH1A1 (0.58) | MMP1CTSKCTSLCTSSPSMB5 | |
| SCHEMBL9832852 | 0.80 | MMP1 (0.56) | MMP1 | |
| SCHEMBL19708144 | 0.79 | CAPN1 (0.56) | CTSKCTSLRENPSMB5CAPN1 | |
| SCHEMBL19707918 | 0.79 | CAPN1 (0.56) | CTSKCTSLRENPSMB5CAPN1 | |
| SCHEMBL9517376 | 0.79 | PSMB5 (0.69) | MMP1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |