Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495377 | 0.77 | GAA (0.42) | NPC1RAB9AMAPTTSHRHSD17B10 | |
| SCHEMBL9681520 | 0.77 | NPC1 (0.58) | NPC1RAB9AMAPTTSHRHSD17B10 | |
| SCHEMBL27690103 | 0.76 | KMT2A (0.60) | MAPTTSHRHSD17B10HTTL3MBTL1 | |
| SCHEMBL4431148 | 0.76 | GABRA2 (0.39) | NPC1RAB9AGAACYP2C9ALDH1A1 | |
| SCHEMBL28298003 | 0.75 | KDM4E (0.49) | NPC1MAPTTSHRHSD17B10HTT | |
| SCHEMBL10919111 | 0.74 | ELOVL1 (0.45) | NPC1MAPTTSHRHSD17B10HTT | |
| SCHEMBL10584537 | 0.74 | GABRA2 (0.45) | MAPTMAPK1ALDH1A1KMT2AKDM4E | |
| SCHEMBL9832518 | 0.74 | ALDH1A1 (0.56) | NPC1RAB9AMAPTTSHRHSD17B10 | |
| SCHEMBL28767728 | 0.74 | MAPT (0.52) | MAPTTSHRHSD17B10HTTL3MBTL1 | |
| SCHEMBL11397324 | 0.73 | GAA (0.72) | NPC1RAB9AHSD17B10L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269806-B1 | PHENYLPYRAZOLE CARBONIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS AND ANTIDOTES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0269806-A1 | Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-08 | — | — | EP | disclosed |