SCHEMBL9832268

SCHEMBL9832268

Cc1cc(O)c(C(C)(C)C)c(Sc2cc(C)cc(OP(O)O)c2C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.34
ALOX15 P16050 2/20 0.34
GAA P10253 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431321 0.83 ALOX15 (0.47) TP53ALOX15GAAMAPTKMT2A
SCHEMBL98264 0.83 ALOX15 (0.47) TP53ALOX15GAAMAPTKMT2A
SCHEMBL11118495 0.71 TP53 (0.42) TP53ALOX15
SCHEMBL9742612 0.68 SELL (0.52) TP53ALOX15GAAMAPTKMT2A
SCHEMBL9008249 0.66 ALOX15 (0.69) TP53ALOX15GAAMAPTALDH1A1
SCHEMBL11066924 0.65 TP53 (0.54) TP53ALOX15ALDH1A1LMNAHPGD
SCHEMBL18786292 0.64
SCHEMBL29131700 0.63 ALDH1A1 (0.32) ALOX15GAAALDH1A1LMNAHPGD
SCHEMBL28413643 0.63 ALOX15 (0.36) TP53ALOX15MAPTALDH1A1LMNA
SCHEMBL10487308 0.63 SMN1; SMN2 (0.36) ALDH1A1SMN1; SMN2HIF1APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0217149-B1 POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-01-30 EP disclosed
EP-0118578-A1 Polyethers containing 2,2,6,6-tetramethyl piperidinyl carboxylic acid ester groups and synthetic resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1984-09-19 EP disclosed