Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831860 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPK1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL9831782 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPK1KDM4EPOLBTDP1 | |
| SCHEMBL9833575 | 0.88 | ACLY (0.43) | ALDH1A1MAPK1KDM4EPOLBTDP1 | |
| SCHEMBL9832261 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPK1KDM4EPOLBTDP1 | |
| SCHEMBL9832673 | 0.87 | TSHR (0.50) | ALDH1A1POLBTDP1SMN1; SMN2TSHR | |
| SCHEMBL9832028 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MAPK1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL9831230 | 0.86 | SLC40A1 (0.39) | ALDH1A1MAPK1KDM4EPOLBTDP1 | |
| SCHEMBL9832696 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPK1KDM4EPOLBTDP1 | |
| SCHEMBL8358999 | 0.83 | TSHR (0.45) | ALDH1A1MAPK1KDM4EPOLBSLC40A1 | |
| SCHEMBL9832825 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPK1KDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |