Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.60 |
| ▸ | MME | P08473 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832293 | 1.00 | ACE (0.64) | ACEFOLH1CTSLPSMB5MME | |
| SCHEMBL8499364 | 0.94 | ACE (0.57) | ACEFOLH1CTSLPSMB5MME | |
| SCHEMBL10656896 | 0.93 | CTSL (0.70) | ACECTSLPSMB5MMEPTPN1 | |
| SCHEMBL2735614 | 0.93 | CTSL (0.70) | ACECTSLPSMB5MMEPTPN1 | |
| SCHEMBL4364597 | 0.89 | PTPN1 (0.64) | ACECTSLMMEPTPN1CA2 | |
| SCHEMBL9830474 | 0.88 | PSMB5 (0.72) | FOLH1CTSLPSMB5MME | |
| SCHEMBL9830466 | 0.88 | PSMB5 (0.72) | FOLH1CTSLPSMB5MME | |
| SCHEMBL10953342 | 0.87 | CA2 (0.60) | CTSLPSMB5PTPN1CA2 | |
| SCHEMBL8520566 | 0.87 | PTPN1 (0.72) | ACECTSLMMEPTPN1CA2 | |
| SCHEMBL3497780 | 0.87 | PTPN1 (0.72) | ACECTSLMMEPTPN1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |