Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982134 | 0.88 | NR1H2 (0.38) | NR1H2NR1H3ELANECTSG | |
| SCHEMBL983253 | 0.86 | NR1H2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL12816417 | 0.85 | NR1H2 (0.46) | NR1H2NR1H3ELANECTSG | |
| SCHEMBL983060 | 0.80 | GABRA1 (0.35) | — | |
| SCHEMBL8674511 | 0.78 | ELANE (0.38) | KDM4EALDH1A1GAAHPGDNR1H2 | |
| SCHEMBL4527020 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDNR1H2 | |
| SCHEMBL982518 | 0.77 | NR1H2 (0.42) | NR1H2NR1H3ELANECTSG | |
| SCHEMBL982139 | 0.75 | MGLL (0.37) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL981930 | 0.75 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL983504 | 0.74 | NR1H2 (0.50) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-3320065-A1 | COMPOSITION AND METHOD FOR PREVENTING OR REDUCING ENGINE KNOCK AND PRE-IGNITION IN HIGH COMPRESSION SPARK IGNITION ENGINES | ExxonMobil Research and Engineering Company (US) | 2018-05-16 | — | — | EP | disclosed |
| WO-2017007669-A1 | COMPOSITION AND METHOD FOR PREVENTING OR REDUCING ENGINE KNOCK AND PRE-IGNITION IN HIGH COMPRESSION SPARK IGNITION ENGINES | EXXONMPBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-01-12 | — | — | WO | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| US-8921290-B2 | Gear oil compositions | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130184191-A1 | GEAR OIL COMPOSITIONS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-07-18 | — | — | US | disclosed |
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2275406-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | CPS1, PHGDH, APEH | KDM4E 1003/4885ALDH1A1 2204/4885GAA 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.