SCHEMBL982518

SCHEMBL982518

CCCCc1ccccc1-c1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
LIPG Q9Y5X9 1/20 0.39
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
TLR8 Q9NR97 1/20 0.34
PPARA Q07869 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
GPR3 P46089 1/20 0.33
TYR P14679 1/20 0.33
CYSLTR2 Q9NS75 3/20 0.32
CYSLTR1 Q9Y271 3/20 0.32
ALOX5 P09917 1/20 0.32
PTGS2 P35354 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL981930 0.95 NR1H2 (0.48) NR1H2NR1H3LIPGTLR8PPARA
SCHEMBL17802343 0.93 NR1H2 (0.50) NR1H2NR1H3LIPGPPARAGPR3
SCHEMBL983504 0.93 NR1H2 (0.50) NR1H2NR1H3LIPGPPARAGPR3
SCHEMBL983253 0.89 NR1H2 (0.34) NR1H2NR1H3LIPGPPARA
SCHEMBL982134 0.87 NR1H2 (0.38) NR1H2NR1H3LIPGCYP3A4CYP2D6
SCHEMBL982139 0.82 MGLL (0.37) NR1H2NR1H3CYP2D6
SCHEMBL12816417 0.82 NR1H2 (0.46) NR1H2NR1H3LIPGPPARAELANE
SCHEMBL11292680 0.80 NR1H2 (0.34) NR1H2NR1H3LIPG
SCHEMBL5893292 0.80 GPR3 (0.38) NR1H2NR1H3LIPGCYP3A4CYP2D6
SCHEMBL11045790 0.79 NR1H2 (0.39) NR1H2NR1H3LIPGCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4291592-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP America Inc. (US) 2023-12-20 EP disclosed
WO-2022173532-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2022-08-18 WO disclosed
EP-3606971-B1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2022-01-12 EP disclosed
US-20200181359-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2020-06-11 US disclosed
US-10597511-B2 Reactive flame retardant blends for flexible polyurethane foam ICL-IP AMERICA INC. (US) 2020-03-24 US disclosed
EP-3606971-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP America Inc. (US) 2020-02-12 EP disclosed
WO-2019060035-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2019-03-28 WO disclosed
US-20190085151-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP AMERICA INC. 2019-03-21 US disclosed
EP-2275406-B1 PROCESS FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2018-11-28 EP disclosed
EP-2630482-B1 Method for the detection of sulphur containing species. UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) 2017-11-29 EP disclosed
US-9448212-B2 Method for the detection of sulphur containing phosphorylating agents UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2016-09-20 US disclosed
US-9233918-B2 Isocyanate production process ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-12 US disclosed
WO-2015142613-A1 PHOSPHATE ESTER-MODIFIED CLAY COMPOSITION, METHOD OF PRODUCING THE SAME AND FLAME-RETARDED PVC NANOCOMPOSITE, CONTAINING THE SAME ICL-IP AMERICA INC. (US) 2015-09-24 WO disclosed
US-20130224873-A1 METHOD AND DEVICE FOR THE DETECTION OF SULPHUR CONTAINING SPECIES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED 2013-08-29 US disclosed
EP-2630482-A2 METHOD AND DEVICE FOR THE DETECTION OF SULPHUR CONTAINING SPECIES University College Cardiff Consultants, Ltd. (GB) 2013-08-28 EP disclosed
WO-2012052746-A2 METHOD AND DEVICE FOR THE DETECTION OF SULPHUR CONTAINING SPECIES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-04-26 WO disclosed
US-20110092731-A1 ISOCYANATE PRODUCTION PROCESS ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-04-21 US disclosed
EP-2275406-A1 PROCESS FOR PRODUCING ISOCYANATE Asahi Kasei Chemicals Corporation (JP) 2011-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092731-A1 ISOCYANATE PRODUCTION PROCESS CPS1, PHGDH, APEH NR1H2 4195/4885NR1H3 4172/4885LIPG 28/4885
US-20130224873-A1 METHOD AND DEVICE FOR THE DETECTION OF SULPHUR CONTAINING SPECIES TST, MPST, SPR NR1H2 4678/4885NR1H3 4592/4885LIPG 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.