Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832609 | 0.84 | REN (0.71) | RENCTSSCTSK | |
| SCHEMBL6448979 | 0.81 | CTSS (0.56) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9848334 | 0.81 | CTSS (0.56) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL8536013 | 0.81 | CTSS (0.56) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL5709574 | 0.80 | CTSS (0.53) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9831856 | 0.79 | CTSS (0.50) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7265417 | 0.79 | CTSS (0.52) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7266599 | 0.78 | REN (0.58) | RENCTSSCTSK | |
| SCHEMBL7272241 | 0.78 | REN (0.58) | RENCTSSCTSK | |
| SCHEMBL6696371 | 0.78 | REN (0.58) | RENCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |