Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522634 | 1.00 | KMT2A (0.49) | KMT2AMEN1CYP1A2KIF11RIPK1 | |
| SCHEMBL22445447 | 1.00 | KMT2A (0.49) | KMT2AMEN1CYP1A2KIF11RIPK1 | |
| SCHEMBL7289002 | 0.84 | KIF11 (0.42) | KMT2AMEN1CYP1A2KIF11DAO | |
| SCHEMBL7289007 | 0.84 | KIF11 (0.42) | KMT2AMEN1CYP1A2KIF11DAO | |
| SCHEMBL9832437 | 0.81 | CHRM2 (0.40) | KMT2AMEN1KIF11RIPK1CHRM2 | |
| SCHEMBL27814402 | 0.79 | HPGD (0.41) | KMT2AMEN1CYP1A2KIF11DAO | |
| SCHEMBL9561446 | 0.79 | RIPK1 (0.42) | KMT2AMEN1KIF11RIPK1DAO | |
| SCHEMBL599752 | 0.77 | DAO (0.43) | KMT2AMEN1CYP1A2KIF11DAO | |
| SCHEMBL41617 | 0.77 | DAO (0.43) | KMT2AMEN1CYP1A2KIF11DAO | |
| SCHEMBL1421302 | 0.77 | DAO (0.43) | KMT2AMEN1CYP1A2KIF11DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1021051-C | THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING SAME | TANABE SEIYAKU CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| CN-1030584-A | Novel thiophene derivant and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-01-25 | — | — | CN | disclosed |
| EP-0297782-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |