Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431669 | 0.85 | MAPT (0.44) | PTGS1PTGS2RAB9AKDM4ELMNA | |
| SCHEMBL10431928 | 0.83 | MAPK1 (0.58) | PTGS1PTGS2RAB9APOLBKDM4E | |
| SCHEMBL10431971 | 0.81 | TDP1 (0.45) | PTGS1PTGS2RAB9APOLBKDM4E | |
| SCHEMBL10913603 | 0.74 | L3MBTL1 (0.45) | RAB9ALMNAL3MBTL1GAATDP1 | |
| SCHEMBL10431757 | 0.74 | LMNA (0.49) | RAB9APOLBKDM4ELMNAL3MBTL1 | |
| SCHEMBL31040146 | 0.73 | PTGS1 (1.00) | PTGS1PTGS2RAB9APOLBKDM4E | |
| SCHEMBL10431906 | 0.71 | GAA (0.48) | RAB9APOLBKDM4ELMNAL3MBTL1 | |
| SCHEMBL7981079 | 0.71 | PTGS1 (0.67) | PTGS1PTGS2RAB9APOLBKDM4E | |
| SCHEMBL7981077 | 0.71 | PTGS1 (0.58) | PTGS1PTGS2POLBKDM4ELMNA | |
| SCHEMBL655938 | 0.71 | MAPT (0.58) | PTGS2RAB9AKDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3251582-A | — | — | None | — | — | JP | disclosed |
| JP-H03251582-A | IMIDAZO(1,2-A)PYRIDYL COMPOUND | TAKEDA CHEM IND LTD | 1991-11-11 | — | — | JP | disclosed |
| EP-0383319-A2 | Imidazopyridines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-22 | — | — | EP | disclosed |