Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.50 |
| ▸ | TUBB | P07437 | 5/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177364 | 0.81 | KMT2A (0.51) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL4797626 | 0.81 | TUBB4A (0.50) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL14216108 | 0.80 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL11343727 | 0.80 | TSHR (0.48) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL11558866 | 0.80 | TSHR (0.48) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL11348095 | 0.80 | TSHR (0.48) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL976684 | 0.79 | CYP1A2 (0.63) | PDE4APDE4BPDE4CPDE4DTPMT | |
| SCHEMBL30413049 | 0.79 | CYP1A2 (0.63) | PDE4APDE4BPDE4CPDE4DTPMT | |
| SCHEMBL10429070 | 0.78 | TPMT (0.50) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL10920836 | 0.78 | ALDH1A1 (0.48) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321544-B | Chiral quaternary carbon cyanide and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2023-05-26 | — | — | CN | disclosed |
| CN-112321544-A | Chiral quaternary carbon cyanide and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2021-02-05 | — | — | CN | disclosed |
| EP-0281854-B1 | 4-CHLORO-OXAZOLES, METHOD FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-11 | — | — | EP | disclosed |
| EP-0281854-A1 | 4-Chloro-oxazoles, method for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-14 | — | — | EP | disclosed |
| US-4371606-A | 2-(Halogenomethyl-phenyl)-4-halogeno-oxaxole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0041674-A2 | 2-(Trichloro-methyl-phenyl)-4-halogen-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-16 | — | — | EP | disclosed |