Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 9/20 | 0.36 |
| ▸ | CDK8 | P49336 | 9/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 8/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292871 | 1.00 | ABCC9 (0.46) | ABCC9IDO1CCNCCDK8HASPIN | |
| SCHEMBL7292872 | 1.00 | ABCC9 (0.46) | ABCC9IDO1CCNCCDK8HASPIN | |
| SCHEMBL9042195 | 0.77 | ABCC9 (0.49) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL9042201 | 0.77 | ABCC9 (0.49) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL9042189 | 0.77 | ABCC9 (0.49) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL7253517 | 0.76 | IDO1 (0.49) | ABCC9IDO1L3MBTL1KCNE1KCNQ1 | |
| SCHEMBL10644246 | 0.76 | IDO1 (0.49) | ABCC9IDO1L3MBTL1KCNE1KCNQ1 | |
| SCHEMBL10644259 | 0.76 | IDO1 (0.49) | ABCC9IDO1L3MBTL1KCNE1KCNQ1 | |
| SCHEMBL9363850 | 0.75 | ABCC9 (0.47) | ABCC9 | |
| SCHEMBL9363847 | 0.75 | ABCC9 (0.47) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205292-B1 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1991-11-06 | — | — | EP | claimed |
| US-4904784-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-02-27 | — | — | US | claimed |
| EP-0205292-A2 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-12-17 | — | — | EP | claimed |
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |
| EP-0205292-B1 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| US-4904784-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4812459-A | PYRANOPYRIDINES | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0205292-A2 | Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-12-17 | — | — | EP | disclosed |