Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832626 | 0.86 | CNR2 (0.53) | MEN1KMT2AGBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9833355 | 0.85 | GBA1 (0.73) | MEN1KMT2AGBA1ALDH1A1PKM | |
| SCHEMBL14606888 | 0.79 | GBA1 (0.59) | THRBMEN1KMT2AGBA1ALDH1A1 | |
| SCHEMBL14606884 | 0.79 | GBA1 (0.59) | THRBMEN1KMT2AGBA1ALDH1A1 | |
| SCHEMBL9833718 | 0.78 | KMT2A (0.51) | MEN1KMT2AGBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13797000 | 0.77 | THRB (0.57) | THRBMEN1KMT2AGBA1ALDH1A1 | |
| SCHEMBL14837537 | 0.77 | HTR2C (0.57) | THRBMEN1KMT2AGBA1ALDH1A1 | |
| SCHEMBL9833885 | 0.77 | GBA1 (0.55) | THRBMEN1KMT2AGBA1ALDH1A1 | |
| SCHEMBL14842670 | 0.77 | ALDH1A1 (0.58) | THRBMEN1KMT2AGBA1ALDH1A1 | |
| SCHEMBL27900130 | 0.76 | TBXA2R (0.53) | THRBMEN1KMT2AGBA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015711-B | Cycloalkaho [1,2-b] indole-sulphonamides | BAYER AG (DE) | 1992-03-04 | — | — | CN | disclosed |
| EP-0242518-B1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0242518-A1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| CN-87100773-A | Cycloalkanes is [1,2-b] indoles-sulfamide compound also | — | 1987-09-02 | — | — | CN | disclosed |