Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833253 | 0.89 | TSHR (0.35) | TSHREGFRALDH1A1 | |
| SCHEMBL9833689 | 0.88 | ACLY (0.36) | ACLYTSHRMETAP2HTR6EGFR | |
| SCHEMBL9832660 | 0.87 | NHERF1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL9831009 | 0.86 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL9832877 | 0.86 | ACLY (0.47) | ACLYTSHRMETAP2SORT1ALDH1A1 | |
| SCHEMBL9831761 | 0.85 | TSHR (0.35) | ACLYTSHRMETAP2HTR6USP2 | |
| SCHEMBL9831934 | 0.82 | TSHR (0.51) | TSHRUSP2ALDH1A1 | |
| SCHEMBL9832689 | 0.82 | ACLY (0.39) | ACLYSORT1EGFRALDH1A1 | |
| SCHEMBL9833655 | 0.82 | ACLY (0.39) | ACLYSORT1EGFRALDH1A1 | |
| SCHEMBL9834365 | 0.81 | METAP2 (0.33) | ACLYTSHRMETAP2SORT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |