Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833475 | 0.90 | ALDH1A1 (0.62) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL2372546 | 0.88 | ALDH1A1 (0.83) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL10375728 | 0.86 | ALDH1A1 (0.80) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL12819436 | 0.84 | ALDH1A1 (0.96) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL13297951 | 0.84 | ALDH1A1 (0.90) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL9015380 | 0.83 | KDM4E (0.58) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL2192735 | 0.83 | MAPK1 (0.71) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL9594597 | 0.83 | KDM4E (0.58) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL1711883 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL8660130 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242518-B1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0242518-A1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |