SCHEMBL983301

SCHEMBL983301

C=CCc1ncc2ccccc2n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
GPR3 P46089 1/20 0.38
EGFR P00533 1/20 0.38
CYP1A2 P05177 2/20 0.37
TLR8 Q9NR97 1/20 0.36
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR3A P46098 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
ALDH1A1 P00352 2/20 0.35
GLA P06280 1/20 0.35
HPGD P15428 1/20 0.35
ACHE P22303 1/20 0.35
PDE10A Q9Y233 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28415502 0.80 KDM4E (0.37) KDM4EGPR3EGFRCYP1A2PDGFRB
SCHEMBL6916239 0.79 KDM4E (0.36) KDM4EGPR3EGFRCYP1A2TLR8
SCHEMBL28158746 0.79 KDM4E (0.36) KDM4EGPR3EGFRCYP1A2TLR8
SCHEMBL882940 0.79 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2PDGFRB
SCHEMBL290894 0.79 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2PDGFRB
SCHEMBL1514912 0.75 CYP1A2 (0.42) KDM4EGPR3EGFRCYP1A2TLR8
SCHEMBL9971234 0.75 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2PDGFRB
SCHEMBL2263641 0.75 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2TLR8
SCHEMBL874900 0.75 KMT2A (0.44) KDM4EGPR3EGFRCYP1A2PDGFRB
SCHEMBL6597830 0.75 SORD (0.47) KDM4EGPR3EGFRCYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3138890-B1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE METAL OXIDES, MODIFIED FORMATION SURFACES, AND METHODS FOR MAKING AND USING SAME LUBRIZOL CORP (US) 2020-11-11 EP claimed
EP-3071666-B1 METHOD AND COMPOSITION FOR CONSOLIDATING SOLID MATERIALS DURING SUBTERRANEAN TREATMENT OPERATIONS LUBRIZOL CORP (US) 2020-08-12 EP claimed
CN-105745300-B Method of consolidating solid materials during subterranean treatment operations 韦特福特科技控股有限责任公司 2019-10-22 CN claimed
EP-3486296-A1 A METHOD AND SYSTEM USING ZETA POTENTIAL ALTERING COMPOSITIONS AS AGGREGATING REAGENTS FOR SAND CONTROL The Lubrizol Corporation (US) 2019-05-22 EP claimed
US-10202836-B2 Methods for fracturing formations using aggregating compositions THE LUBRIZOL CORPORATION (US) 2019-02-12 US claimed
US-10040991-B2 Zeta potential modifiers to decrease the residual oil saturation THE LUBRIZOL CORPORATION (US) 2018-08-07 US claimed
US-20180209260-A1 Method to Consolidate Solid Materials During Subterranean Treatment Operations LUBRIZOL CORP (US) 2018-07-26 US claimed
US-9945220-B2 Methods and system for creating high conductivity fractures THE LUBRIZOL CORPORATION (US) 2018-04-17 US claimed
EP-3303504-A1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE SOLID COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME Lubrizol Oilfield Solutions, Inc. (US) 2018-04-11 EP claimed
US-9938453-B2 Particulate aggregating and surface modification with improved hydrocarbon fluid flow through the aggregated particulates and over solid surface reagents and methods for making and using same Sumisaujana TCM Chemicals Sdn. Bhd. (MY) 2018-04-10 US claimed
US-20110005756-A1 USE OF ZETA POTENTIAL MODIFIERS TO DECREASE THE RESIDUAL OIL SATURATION CLEARWATER INTERNATIONAL, LLC (US) 2011-01-13 US claimed
US-20100292108-A1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE METAL-OXIDES, MODIFIED FORMATION SURFACES, AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2010-11-18 US claimed
EP-2251394-A2 Aggregating compositions, modified particulate metal-oxides, modified formation surfaces, and methods for making and using same Clearwater International LLC (US) 2010-11-17 EP claimed
EP-2251395-A1 Methods for increase gas production and load recovery Clearwater International LLC (US) 2010-11-17 EP claimed
US-20100212905-A1 METHOD AND SYSTEM USING ZETA POTENTIAL ALTERING COMPOSITIONS AS AGGREGATING REAGENTS FOR SAND CONTROL WEATHERFORD/LAMB, INC. (US) 2010-08-26 US claimed
WO-2010084009-A1 A METHOD AND SYSTEM USING ZETA POTENTIAL ALTERING COMPOSITIONS AS AGGREGATING REAGENTS FOR SAND CONTROL WEATHERFORD/LAMB, INC (US) 2010-07-29 WO claimed
US-20090275488-A1 METHODS FOR INCREASE GAS PRODUCTION AND LOAD RECOVERY CLEARWATER INTERNATIONAL, LLC (US) 2009-11-05 US claimed
US-20080257553-A1 Aggregating reagents, modified particulate metal-oxides and proppants CLEARWATER INTERNATIONAL, LLC 2008-10-23 US claimed
US-7392847-B2 Aggregating reagents, modified particulate metal-oxides, and methods for making and using same CLEARWATER INTERNATIONAL, LLC (US) 2008-07-01 US claimed
US-20070131425-A1 Aggregating reagents, modified particulate metal-oxides, and methods for making and using same CLEARWATER INTERNATIONAL, LLC 2007-06-14 US claimed