Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415502 | 0.84 | KDM4E (0.37) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL28158746 | 0.83 | KDM4E (0.36) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL983301 | 0.79 | KDM4E (0.38) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL882940 | 0.76 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL460159 | 0.75 | MAPK1 (0.41) | KDM4EPDE10AHTR3AHRH4ALDH1A1 | |
| SCHEMBL6597830 | 0.72 | SORD (0.47) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL1514912 | 0.72 | CYP1A2 (0.42) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL874900 | 0.72 | KMT2A (0.44) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL2263641 | 0.72 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2PDE10A | |
| SCHEMBL9971234 | 0.72 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259192-A1 | Method for cleaving the human growth hormone gh | IBFB GMBH PRIVATES INSTITUT FUR BIOMEDIZINISCHE FORSCHUNG UND BERATUNG (DE) | 2004-12-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259192-A1 | Method for cleaving the human growth hormone gh | MMP3, MMP25, MMP17 | KDM4E 3443/4885GPR3 584/4885EGFR 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.