Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.40 |
| ▸ | BHMT | Q93088 | 2/20 | 0.34 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441410 | 0.81 | ANPEP (0.46) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL7281691 | 0.81 | ANPEP (0.46) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL7362253 | 0.79 | CYP1A2 (0.45) | ANPEPDNPEPCYP2D6RNPEP | |
| Hydrochloric Acid SCHEMBL7441882 | 0.79 | ANPEP (0.44) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL29322832 | 0.74 | TRPV1 (0.41) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL19724156 | 0.74 | CYP2D6 (0.42) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL7378006 | 0.74 | ALDH1A1 (0.43) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL29322856 | 0.74 | CYP2D6 (0.42) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL10893754 | 0.73 | TSHR (0.45) | ANPEPDNPEPTSHRALDH1A1MAPK1 | |
| SCHEMBL1114588 | 0.72 | CTSL (0.42) | BHMTBHMT2GBA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |