Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | CASP7 | P55210 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551049 | 0.87 | CSNK2A2 (0.52) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL9833244 | 0.79 | MAOB (0.49) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL18287650 | 0.71 | RXRA (0.53) | ABCB1 | |
| SCHEMBL18287649 | 0.71 | RXRA (0.53) | ABCB1 | |
| SCHEMBL25233130 | 0.69 | ACHE (0.81) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL4650608 | 0.69 | CSNK2A2 (0.82) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL30807156 | 0.69 | CYP3A4 (1.00) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL4650077 | 0.69 | CYP3A4 (1.00) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL25233304 | 0.69 | KDM4E (0.56) | MAPTKDM4ECYP3A4HSD17B10TP53 | |
| SCHEMBL25205540 | 0.68 | ACHE (0.66) | MAPTKDM4ECYP3A4HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237986-B1 | FLAVONE CARBOXYLIC ACID DERIVATIVES | Shudo, Koichi, Prof. Dr. (JP) | 1991-10-02 | — | — | EP | claimed |