Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833151 | 0.95 | IDO1 (0.40) | IDO1MAPTPOLBMEN1ALDH1A1 | |
| SCHEMBL9831794 | 0.91 | PTGS1 (0.42) | MAPTPOLBMEN1KMT2AKCNJ6 | |
| SCHEMBL9831545 | 0.90 | RIPK1 (0.41) | MAPTPOLBALDH1A1KDM4EKCNJ6 | |
| SCHEMBL9316748 | 0.90 | MAPT (0.44) | MAPTPOLBALDH1A1KDM4EPTGS1 | |
| SCHEMBL9832438 | 0.88 | MAPT (0.45) | MAPTPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL9176651 | 0.88 | IDO1 (0.47) | IDO1MAPTPOLBMEN1ALDH1A1 | |
| SCHEMBL9833141 | 0.88 | KCNJ6 (0.41) | MAPTPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL9833803 | 0.87 | RAB9A (0.42) | MAPTPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL9834929 | 0.87 | CCNA2 (0.41) | MAPTPOLBALDH1A1KCNJ6KCNJ5 | |
| SCHEMBL9319611 | 0.86 | MAPT (0.43) | MAPTPOLBALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274443-B1 | HETEROARYL 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-05-29 | — | — | EP | disclosed |
| US-4816467-A | BACTERICIDES, VIRICIDES | FARMITALIA CARLO ERBA S.R.L (IT) | 1989-03-28 | — | — | US | disclosed |