Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835821 | 0.84 | TP53 (0.34) | POLBHPGDTSHRCYP3A4MAPK1 | |
| SCHEMBL9834736 | 0.83 | TDP1 (0.37) | POLBHPGDTSHRCYP3A4MAPK1 | |
| SCHEMBL9833447 | 0.80 | TSHR (0.37) | POLBHPGDTSHRCYP3A4MAPK1 | |
| SCHEMBL9834882 | 0.77 | TDP1 (0.34) | POLBTSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL9836034 | 0.76 | TDP1 (0.35) | POLBHPGDTSHRCYP3A4MAPK1 | |
| SCHEMBL9835333 | 0.74 | SLC6A9 (0.32) | POLBTSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL10453485 | 0.73 | TSHR (0.35) | POLBHPGDTSHRCYP3A4MAPK1 | |
| SCHEMBL9835267 | 0.73 | TDP1 (0.33) | POLBHPGDTSHRCYP3A4MAPK1 | |
| SCHEMBL9835887 | 0.71 | CYP3A4 (0.37) | POLBTSHRCYP3A4LMNAMEN1 | |
| SCHEMBL9482770 | 0.69 | TDP1 (0.36) | POLBTSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126430-B1 | PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0126430-A2 | Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |