Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10376017 | 0.98 | MAOB (0.40) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL9832041 | 0.82 | CYP1A2 (0.39) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL9831475 | 0.81 | IDO1 (0.31) | MAOBIDO1 | |
| SCHEMBL9835029 | 0.76 | MAOB (0.39) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL5179243 | 0.76 | PGR (0.44) | — | |
| SCHEMBL9834101 | 0.75 | MAOB (0.38) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL9831472 | 0.75 | IDO1 (0.38) | MAPTTP53IDO1 | |
| Hydrochloric Acid SCHEMBL10374033 | 0.74 | PGR (0.43) | — | |
| SCHEMBL24019918 | 0.74 | MAPT (0.46) | MAOBMAPTTP53LMNATHRB | |
| SCHEMBL18854108 | 0.74 | MAPT (0.46) | MAOBMAPTTP53LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161632-B1 | PYRROLO-BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4963686-A | INTERMEDIATES FOR INOTROPIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-16 | — | — | US | disclosed |