SCHEMBL9831475

SCHEMBL9831475

CCC(CC)C1C(=O)Nc2cc(N)c(N)cc21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9831495 0.83 CYP1A2 (0.37)
SCHEMBL9833951 0.83 CYP1A2 (0.37)
Hydrochloric Acid SCHEMBL10376017 0.80 MAOB (0.40) MAOB
SCHEMBL9833436 0.78 BRPF1 (0.30) MAOB
SCHEMBL10470471 0.72 IDO1 (0.41) IDO1
SCHEMBL9833431 0.72 CHRNB2 (0.40)
SCHEMBL9831472 0.71 IDO1 (0.38) IDO1
Hydrochloric Acid SCHEMBL10374033 0.70 PGR (0.43)
SCHEMBL9831075 0.70 KDM4E (0.40)
SCHEMBL10472852 0.69 MAPT (0.42) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161632-B1 PYRROLO-BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND INTERMEDIATES Roche Diagnostics GmbH (DE) 1991-04-10 EP disclosed
US-4963686-A INTERMEDIATES FOR INOTROPIC AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1990-10-16 US disclosed