Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.66 |
| ▸ | HTR1A | P08908 | 5/20 | 0.66 |
| ▸ | TP53 | P04637 | 5/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.66 |
| ▸ | KDM1A | O60341 | 4/20 | 0.66 |
| ▸ | DRD2 | P14416 | 4/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.66 |
| ▸ | DRD1 | P21728 | 4/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.66 |
| ▸ | DRD3 | P35462 | 4/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.66 |
| ▸ | THPO | P40225 | 4/20 | 0.66 |
| ▸ | MTOR | P42345 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prothipendyl SCHEMBL29393787 | 0.86 | CYP2D6 (0.72) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Prothipendyl SCHEMBL145059 | 0.86 | CYP2D6 (0.72) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Prothipendyl SCHEMBL1649843 | 0.85 | CYP2D6 (0.70) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Prothipendyl SCHEMBL5705613 | 0.85 | LMNA (0.72) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| SCHEMBL26238573 | 0.81 | CYP2D6 (0.64) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Promazine SCHEMBL123419 | 0.81 | CYP2D6 (0.94) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Promazine SCHEMBL9052694 | 0.80 | CYP2D6 (1.00) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Promazine SCHEMBL29392545 | 0.80 | CYP2D6 (1.00) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Promazine SCHEMBL140489 | 0.80 | CYP2D6 (1.00) | CYP2D6CYP1A2HTR1ATP53CYP2C19 | |
| Promazine SCHEMBL28239574 | 0.79 | CYP2D6 (0.91) | CYP2D6CYP1A2HTR1ATP53CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140709-B1 | 5-LIPOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1991-04-03 | — | — | EP | disclosed |