Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834135 | 0.88 | KMT2A (0.34) | ALDH1A1SMN1; SMN2LMNAKMT2AFFAR4 | |
| SCHEMBL9832446 | 0.87 | ALDH1A1 (0.33) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9831353 | 0.83 | KMT2A (0.32) | CCR4KMT2AMEN1 | |
| SCHEMBL9831850 | 0.81 | TSHR (0.38) | ALDH1A1CCR4KMT2AFFAR4TSHR | |
| SCHEMBL9830852 | 0.79 | ALDH1A1 (0.33) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9830515 | 0.79 | SLC40A1 (0.35) | CCR4KMT2ATSHR | |
| SCHEMBL10665482 | 0.79 | SLC22A12 (0.38) | CCR4ALPLTSHR | |
| SCHEMBL8358795 | 0.78 | SLC40A1 (0.36) | ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL9832422 | 0.78 | L3MBTL1 (0.32) | ALDH1A1LMNAALPLTSHR | |
| SCHEMBL9831382 | 0.77 | MAPT (0.36) | ALDH1A1SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | claimed |