Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833014 | 0.83 | NQO2 (0.41) | ALDH1A1PGRNQO2IDO1TDO2 | |
| SCHEMBL9834389 | 0.78 | PGR (0.41) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL9833162 | 0.74 | PGR (0.41) | PGRIDO1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL9835070 | 0.74 | PGR (0.41) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL9834592 | 0.72 | PGR (0.39) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL9836114 | 0.72 | PGR (0.39) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL9833820 | 0.71 | PGR (0.38) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL9834460 | 0.71 | ATAD2 (0.42) | PGR | |
| SCHEMBL9835252 | 0.70 | PGR (0.40) | ALDH1A1PGRNQO2IDO1MEN1 | |
| SCHEMBL9832702 | 0.69 | TNKS2 (0.45) | ALDH1A1PGRMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |