Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834688 | 0.84 | TRPM8 (0.37) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL9833352 | 0.83 | TDP1 (0.41) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL9834267 | 0.79 | RAB9A (0.38) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL9835076 | 0.74 | EPHX2 (0.42) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL9835307 | 0.72 | NPC1 (0.36) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL10798500 | 0.72 | TRPM8 (0.41) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL9834614 | 0.71 | MEN1 (0.38) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL9834582 | 0.71 | — | — | |
| SCHEMBL9833134 | 0.71 | MEN1 (0.36) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL10870048 | 0.68 | HDAC3 (0.50) | NPC1RAB9APKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211665-B1 | BENZOYL-UREAS HAVING ACARICIDE AND INSECTICIDE ACTIVITY | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| EP-0211665-A2 | Benzoyl-ureas having acaricide and insecticide activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-02-25 | — | — | EP | disclosed |