Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.38 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834476 | 0.84 | TDP1 (0.41) | TDP1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9833962 | 0.83 | NPC1 (0.35) | TDP1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9832964 | 0.78 | TDP1 (0.47) | TDP1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9835209 | 0.75 | TDP1 (0.41) | TDP1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9833042 | 0.73 | TDP1 (0.43) | TDP1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9835239 | 0.72 | PCTP (0.41) | TDP1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9834582 | 0.70 | — | — | |
| SCHEMBL9834942 | 0.69 | NPC1 (0.39) | RAB9ASMN1; SMN2L3MBTL1NPC1PKM | |
| SCHEMBL10777256 | 0.68 | TDP1 (0.53) | TDP1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9834688 | 0.68 | TRPM8 (0.37) | TDP1RAB9ALMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211665-B1 | BENZOYL-UREAS HAVING ACARICIDE AND INSECTICIDE ACTIVITY | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |