Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807380 | 0.81 | HRH1 (0.62) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL623853 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13543173 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL4653824 | 0.76 | CYP2C19 (0.71) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL2466643 | 0.75 | ALDH1A1 (1.00) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL28588022 | 0.73 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL24701104 | 0.72 | HTR6 (0.56) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL14654432 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL14402596 | 0.71 | ALDH1A1 (0.56) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680859 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MAPTPKMHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388429-A4 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |