Sugi Predict

Sugi Predict / Compounds / SCHEMBL9834151

SCHEMBL9834151

SCHEMBL9834151

NC(=O)N(O)CCc1ccc(Cc2ccccc2)o1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 12/20 0.47
▸ CTSL P07711 1/20 0.42
▸ PLA2G10 O15496 1/20 0.39
▸ PLA2G2A P14555 1/20 0.39
▸ HRH1 P35367 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9834288 0.83 ALOX5 (0.59) ALOX5
SCHEMBL9832067 0.80 ALOX5 (0.45) ALOX5
SCHEMBL9833394 0.79 ALOX5 (0.74) ALOX5HRH1
SCHEMBL9831016 0.77 ALOX5 (0.42) ALOX5
SCHEMBL9380345 0.77 ALOX5 (0.54) ALOX5PLA2G10PLA2G2A
SCHEMBL9833184 0.76 ALOX5 (0.51) ALOX5
SCHEMBL9373618 0.76 ALOX5 (0.57) ALOX5
SCHEMBL8814587 0.76 ALOX5 (0.59) ALOX5
SCHEMBL9832426 0.75 ALOX5 (0.71) ALOX5
SCHEMBL9831384 0.75 ALOX5 (0.45) ALOX5HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0388429-A4 FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS — 1991-08-21 — — EP disclosed
EP-0388429-A1 FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1990-09-26 — — EP disclosed
WO-1989004299-A1 FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1989-05-18 — — WO disclosed