Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833391 | 0.97 | MAPT (0.46) | MAPTMEN1POLBKMT2ATP53 | |
| SCHEMBL9831879 | 0.95 | MAPT (0.42) | MAPTMEN1POLBKMT2ATP53 | |
| SCHEMBL9834840 | 0.95 | MAPT (0.44) | MAPTMEN1POLBKMT2ATP53 | |
| SCHEMBL9834096 | 0.94 | MAPT (0.49) | MAPTTP53LMNACNR1CCNA2 | |
| SCHEMBL9831377 | 0.92 | TP53 (0.45) | MAPTMEN1POLBKMT2ATP53 | |
| SCHEMBL9833865 | 0.89 | POLB (0.39) | MAPTMEN1POLBKMT2ATP53 | |
| SCHEMBL9834242 | 0.88 | MAPT (0.50) | MAPTTP53LMNADHODH | |
| SCHEMBL9831991 | 0.87 | MAPT (0.52) | MAPTTP53LMNA | |
| SCHEMBL9316737 | 0.87 | TP53 (0.49) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL9831040 | 0.87 | RIPK1 (0.41) | MAPTMEN1POLBKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274443-B1 | HETEROARYL 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-05-29 | — | — | EP | disclosed |
| US-4816467-A | BACTERICIDES, VIRICIDES | FARMITALIA CARLO ERBA S.R.L (IT) | 1989-03-28 | — | — | US | disclosed |