Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | GCLC | P48506 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834869 | 1.00 | ANPEP (0.41) | ANPEPDNPEPSLC7A5RNPEPLAP3 | |
| SCHEMBL7396177 | 0.79 | CA2 (0.44) | ANPEPDNPEPRNPEPLAP3ERAP1 | |
| SCHEMBL7396180 | 0.79 | CA2 (0.44) | ANPEPDNPEPRNPEPLAP3ERAP1 | |
| SCHEMBL7281691 | 0.78 | ANPEP (0.46) | ANPEPDNPEPSLC7A5RNPEPLAP3 | |
| SCHEMBL7441410 | 0.78 | ANPEP (0.46) | ANPEPDNPEPSLC7A5RNPEPLAP3 | |
| Hydrochloric Acid SCHEMBL7441882 | 0.76 | ANPEP (0.44) | ANPEPDNPEPSLC7A5RNPEPLAP3 | |
| SCHEMBL3167161 | 0.74 | GAA (0.34) | GCLCALDH1A1 | |
| SCHEMBL9831063 | 0.72 | ANPEP (0.46) | ANPEPDNPEPSLC7A5RNPEPLAP3 | |
| SCHEMBL7378006 | 0.71 | ALDH1A1 (0.43) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL19724156 | 0.71 | CYP2D6 (0.42) | ANPEPDNPEPSLC7A5LAP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |