Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.40 |
| ▸ | IL1RN | P18510 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 4/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396177 | 1.00 | CA2 (0.44) | CA2ERAP1ERAP2IL1RNCSNK1E | |
| SCHEMBL3506697 | 0.82 | ERAP1 (0.47) | ERAP1ERAP2IL1RNCSNK1EANPEP | |
| SCHEMBL8270986 | 0.82 | ERAP1 (0.47) | ERAP1ERAP2IL1RNCSNK1EANPEP | |
| Hydrochloric Acid SCHEMBL7435119 | 0.81 | ERAP1 (0.46) | ERAP1ERAP2IL1RNCSNK1EANPEP | |
| SCHEMBL9834732 | 0.79 | ANPEP (0.41) | ERAP1ANPEPLAP3RNPEPDNPEP | |
| SCHEMBL9834869 | 0.79 | ANPEP (0.41) | ERAP1ANPEPLAP3RNPEPDNPEP | |
| SCHEMBL7362253 | 0.76 | CYP1A2 (0.45) | CA2ERAP1ERAP2IL1RNCSNK1E | |
| SCHEMBL7362251 | 0.73 | ERAP1 (0.42) | ERAP1ERAP2IL1RNCSNK1EANPEP | |
| SCHEMBL10764126 | 0.72 | HPGD (0.57) | ALDH1A1 | |
| SCHEMBL302785 | 0.72 | CA2 (0.69) | CA2MMP12MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |