Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583807 | 0.87 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL30583810 | 0.82 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL6904161 | 0.81 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL6904159 | 0.81 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL9833804 | 0.81 | RAB9A (0.44) | NPC1RAB9AKMT2AEPHX1ALDH1A1 | |
| SCHEMBL13156519 | 0.81 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL3089032 | 0.81 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7735034 | 0.80 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9835734 | 0.80 | KMT2A (0.66) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL30583808 | 0.79 | MMP2 (0.56) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211665-B1 | BENZOYL-UREAS HAVING ACARICIDE AND INSECTICIDE ACTIVITY | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| EP-0211665-A2 | Benzoyl-ureas having acaricide and insecticide activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-02-25 | — | — | EP | disclosed |