Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583802 | 0.86 | SSTR3 (0.54) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7735034 | 0.85 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2SSTR3ALDH1A1 | |
| SCHEMBL22289342 | 0.83 | MEN1 (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1MMP2 | |
| SCHEMBL9834832 | 0.81 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1EPHX1 | |
| SCHEMBL30583811 | 0.80 | RAB9A (0.51) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL14117665 | 0.80 | HDAC4 (0.52) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL12156531 | 0.79 | RAB9A (0.62) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL12156569 | 0.79 | RAB9A (0.67) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL3546724 | 0.78 | RAB9A (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27916661 | 0.77 | ALDH1A1 (0.41) | RAB9ANPC1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211665-B1 | BENZOYL-UREAS HAVING ACARICIDE AND INSECTICIDE ACTIVITY | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| EP-0211665-A2 | Benzoyl-ureas having acaricide and insecticide activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-02-25 | — | — | EP | disclosed |