Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834949 | 0.86 | CYP3A4 (0.37) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL10824307 | 0.85 | NAAA (0.33) | HTR2AHTR2CHTR2BXDH | |
| SCHEMBL9528915 | 0.83 | CYP3A4 (0.37) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL7021771 | 0.82 | PPOX (0.40) | ALDH1A1CYP3A4HPGDTDP1DHODH | |
| SCHEMBL9814255 | 0.78 | CUL4A (0.41) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL5846557 | 0.77 | CYP3A4 (0.42) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL10986658 | 0.74 | CA12 (0.36) | ALDH1A1HPGD | |
| SCHEMBL30017045 | 0.74 | CYP3A4 (0.42) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL9851164 | 0.73 | — | — | |
| SCHEMBL15321040 | 0.72 | CYP3A4 (0.46) | ALDH1A1CYP3A4HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |
| EP-0241559-A1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-10-21 | — | — | EP | disclosed |