SCHEMBL7021771

SCHEMBL7021771

CC(C)Oc1cc(N=C=O)c(F)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.40
CSNK2A1 P68400 2/20 0.36
RORC P51449 1/20 0.35
TDP1 Q9NUW8 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NR1I2 O75469 1/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
CYP3A4 P08684 1/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAP2 P11137 1/20 0.33
GAA P10253 2/20 0.33
DHODH Q02127 2/20 0.31
MAPK1 P28482 2/20 0.31
KCNQ3 O43525 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8485419 0.86 ALDH1A1 (0.31) PPOXTDP1ALDH1A1HPGDCYP3A4
SCHEMBL9529407 0.86 TDP1 (0.39) PPOXCSNK2A1RORCTDP1MEN1
SCHEMBL9834949 0.86 CYP3A4 (0.37) TDP1ALDH1A1HPGDCYP3A4KCNQ3
SCHEMBL8579591 0.85 PPOX (0.38) PPOXCSNK2A1RORCTDP1MEN1
SCHEMBL9528915 0.83 CYP3A4 (0.37) TDP1ALDH1A1HPGDCYP3A4
SCHEMBL7003782 0.83 ALDH1A1 (0.47) PPOXTDP1MEN1KMT2AALDH1A1
SCHEMBL9834892 0.82 ALDH1A1 (0.34) TDP1ALDH1A1HPGDCYP3A4DHODH
SCHEMBL10578397 0.81 PPOX (0.52) PPOXTDP1MEN1KMT2AALDH1A1
SCHEMBL9836317 0.79 PPOX (0.40) PPOXRORCTDP1ALDH1A1HPGD
SCHEMBL7247126 0.78 CUL4A (0.41) PPOXRORCTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973395-B1 DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM ISK AMERICAS INC (US) 2003-12-03 EP disclosed
US-6479435-B1 OR DIARYL SULFIDES, 1-(4-CHLORO-2-FLUORO-5-(2-PYRIMIDYLOXY)PHENYL)-4-DIFLUOROMETHY L-3-METHYL-1,4-DIHYDRO-1,2,4-TRIAZOLIN-5-ONE FOR EXAMPLE ISK AMERICAS INCORPORATED 2002-11-12 US disclosed
US-20020161224-A1 Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them PULMAN DAVID A (US) 2002-10-31 US disclosed
US-6333296-B1 FOR CONTRILLING WEEDS ISK AMERICAS INCORPORATED 2001-12-25 US disclosed
US-6303543-B1 Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-10-16 US disclosed
EP-0973395-A4 DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM ISK AMERICAS INC (US) 2001-10-04 EP disclosed
US-6121201-A HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-09-19 US disclosed
EP-0973395-A1 DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM ISK Americas Incorporated (US) 2000-01-26 EP disclosed
WO-1998041093-A1 DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM ISK AMERICAS INCORPORATED (US) 1998-09-24 WO disclosed
EP-0493323-B1 Hydantoin compounds CIBA GEIGY AG (CH) 1997-06-11 EP disclosed
US-4593094-A INTERMEDIATES FOR HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-06-03 US disclosed
US-4579688-A USING PHENYL ISOCYANATE CHEMICAL INTERMEDIATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-04-01 US disclosed
EP-0075267-B1 4-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL)URAZOLS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-15 EP disclosed
EP-0070389-B1 2-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL) HYDANTOINS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-02 EP disclosed
US-4452981-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-06-05 US disclosed
US-4437877-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4427438-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-01-24 US disclosed
EP-0075267-A1 4-(2-Fluoro-4-halo-5-substituted phenyl)urazols, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-30 EP disclosed
EP-0070389-A2 2-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-26 EP disclosed
EP-0069855-A2 N-(2-fluoro-4-halo-5-substituted phenyl)hydantoins, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020161224-A1 Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them HDHD5, DDT, CBR3 PPOX 1376/4885CSNK2A1 1789/4885RORC 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.