Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966470 | 0.92 | ALDH1A1 (0.52) | ALDH1A1BLMKDM4EKMT2AL3MBTL1 | |
| SCHEMBL10994286 | 0.85 | ALDH1A1 (0.55) | ALDH1A1BLMKMT2AL3MBTL1USP2 | |
| SCHEMBL9835390 | 0.82 | KDM4E (0.54) | ALDH1A1BLMKDM4EKMT2AL3MBTL1 | |
| SCHEMBL19721600 | 0.79 | MCHR1 (0.51) | ALDH1A1BLMKDM4EKMT2AL3MBTL1 | |
| SCHEMBL10966952 | 0.77 | KDM4E (0.47) | ALDH1A1BLMKDM4EKMT2AL3MBTL1 | |
| SCHEMBL28544382 | 0.72 | HPGD (0.46) | ALDH1A1BLMKDM4EKMT2AL3MBTL1 | |
| SCHEMBL40501 | 0.71 | GSK3A (0.65) | ALDH1A1KMT2AL3MBTL1USP2TSHR | |
| SCHEMBL9836933 | 0.71 | CCR3 (0.57) | GSK3AGSK3B | |
| SCHEMBL10947749 | 0.70 | KMT2A (0.76) | ALDH1A1KDM4EKMT2AL3MBTL1TSHR | |
| SCHEMBL10993438 | 0.70 | HTT (0.45) | ALDH1A1BLMKDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199485-B1 | INTERMEDIATES AND PROCESS | BEECHAM GROUP PLC (GB) | 1991-10-30 | — | — | EP | claimed |
| EP-0199485-B1 | INTERMEDIATES AND PROCESS | BEECHAM GROUP PLC (GB) | 1991-10-30 | — | — | EP | disclosed |
| EP-0199485-A2 | Intermediates and process | BEECHAM GROUP PLC (GB) | 1986-10-29 | — | — | EP | disclosed |