SCHEMBL9835357

SCHEMBL9835357

CCCCCC=C(C)C(OC(=O)Nc1ccc(Cl)cc1)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 1/20 0.40
CASP1 P29466 1/20 0.39
UTS2R Q9UKP6 1/20 0.39
CNR1 P21554 2/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835438 0.92 MAPT (0.48) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9835939 0.82 MAPT (0.51) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9836956 0.80 RORC (0.42) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9835915 0.79 MAPT (0.46) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9837472 0.78 MAPT (0.48) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9834808 0.76 MAPT (0.54) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9836424 0.76 MAPT (0.52) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9835172 0.75 MAPT (0.52) MAPTL3MBTL1NPC1RAB9AHPGD
SCHEMBL9836764 0.73 SMN1; SMN2 (0.39) MAPTNPC1RAB9AHPGDSMN1; SMN2
SCHEMBL16374745 0.71 RAB9A (0.67) MAPTL3MBTL1NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed