Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9837497 | 0.99 | TBXAS1 (0.55) | TBXAS1ALDH1A1TSHRHDAC8NAPRT | |
| SCHEMBL9834661 | 0.91 | TBXAS1 (0.56) | TBXAS1ALDH1A1TSHRNAPRTMAPT | |
| SCHEMBL9834561 | 0.90 | TBXAS1 (0.59) | TBXAS1ALDH1A1TSHRHDAC8NAPRT | |
| Hydrochloric Acid SCHEMBL10547870 | 0.89 | TBXAS1 (0.58) | TBXAS1ALDH1A1TSHRHDAC8NAPRT | |
| SCHEMBL9834435 | 0.88 | TBXAS1 (0.44) | TBXAS1ALDH1A1TSHRHDAC8MAPT | |
| SCHEMBL9836796 | 0.84 | TBXAS1 (0.43) | TBXAS1ALDH1A1TSHRHDAC8NAPRT | |
| SCHEMBL9836497 | 0.80 | TBXAS1 (0.44) | TBXAS1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL9836574 | 0.78 | TBXAS1 (0.43) | TBXAS1ALDH1A1TSHRHDAC8NAPRT | |
| SCHEMBL9837509 | 0.76 | ALDH1A1 (0.42) | TBXAS1ALDH1A1NAPRTMAPTLMNA | |
| Hydrochloric Acid SCHEMBL10554841 | 0.75 | ALDH1A1 (0.41) | TBXAS1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | claimed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | claimed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |