Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836796 | 0.92 | TBXAS1 (0.43) | TBXAS1MAPTALDH1A1NAPRTTSHR | |
| SCHEMBL9834661 | 0.84 | TBXAS1 (0.56) | TBXAS1MAPTALDH1A1ALOX12NAPRT | |
| SCHEMBL9836514 | 0.82 | TBXAS1 (0.42) | TBXAS1NAPRTHDAC8 | |
| SCHEMBL9836497 | 0.81 | TBXAS1 (0.44) | TBXAS1MAPTALDH1A1ALOX12RAB9A | |
| SCHEMBL9835360 | 0.78 | TBXAS1 (0.56) | TBXAS1MAPTALDH1A1NAPRTTSHR | |
| Hydrochloric Acid SCHEMBL9837497 | 0.77 | TBXAS1 (0.55) | TBXAS1ALDH1A1NAPRTTSHRHDAC8 | |
| SCHEMBL9836173 | 0.76 | ALDH1A1 (0.42) | TBXAS1MAPTALDH1A1NAPRTRAB9A | |
| SCHEMBL9834435 | 0.75 | TBXAS1 (0.44) | TBXAS1MAPTALDH1A1KMT2ATSHR | |
| SCHEMBL9835990 | 0.74 | TBXAS1 (0.72) | TBXAS1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL9836492 | 0.70 | TBXAS1 (0.42) | TBXAS1NAPRTKMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | claimed |