Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GALR2 | O43603 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835516 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL11951437 | 0.90 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL1727258 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL27687932 | 0.89 | NPSR1 (0.50) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL28550137 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL9867338 | 0.88 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL9396485 | 0.87 | MAPT (0.52) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL1724987 | 0.86 | HCAR3 (0.52) | ALDH1A1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL28489151 | 0.85 | NPSR1 (0.47) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 | |
| SCHEMBL1511509 | 0.84 | MAPT (0.49) | ALDH1A1SMN1; SMN2NPSR1HPGDGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190524-B1 | Industrial synthesis of N-[(1'-allyl-2'-pyrrolidinyl)methyl]-2-methoxy-4,5-azimido benzamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1991-03-06 | — | — | EP | claimed |
| EP-0190524-A1 | Industrial synthesis of N-[(1'-allyl-2'-pyrrolidinyl)methyl]-2-methoxy-4,5-azimido benzamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1986-08-13 | — | — | EP | claimed |
| CN-112079741-A | Aminobenzoic acid derivative and preparation method and application thereof | 武汉化工新材料工业技术研究院有限责任公司 | 2020-12-15 | — | — | CN | disclosed |
| US-5026858-A | Used for treating nausea, vomating, gastrointestinal disorders and centarl nervous system | WALTON S.A. (ES) | 1991-06-25 | — | — | US | disclosed |
| EP-0190524-B1 | Industrial synthesis of N-[(1'-allyl-2'-pyrrolidinyl)methyl]-2-methoxy-4,5-azimido benzamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1991-03-06 | — | — | EP | disclosed |
| EP-0190524-A1 | Industrial synthesis of N-[(1'-allyl-2'-pyrrolidinyl)methyl]-2-methoxy-4,5-azimido benzamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1986-08-13 | — | — | EP | disclosed |
| US-4039672-A | EMESIS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1977-08-02 | — | — | US | disclosed |