Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GALR2 | O43603 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951437 | 0.89 | ALDH1A1 (0.51) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL9835516 | 0.88 | ALDH1A1 (0.50) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL1727258 | 0.88 | ALDH1A1 (0.53) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL27687932 | 0.88 | NPSR1 (0.50) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL9835504 | 0.88 | ALDH1A1 (0.50) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL9396485 | 0.86 | MAPT (0.52) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL12215941 | 0.82 | LMNA (0.50) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL1725104 | 0.82 | ALDH1A1 (0.71) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL28496695 | 0.82 | ALDH1A1 (0.48) | ALDH1A1NPSR1LMNAGALR2MITF | |
| SCHEMBL8434561 | 0.82 | KMT2A (0.50) | ALDH1A1NPSR1LMNAGALR2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026858-A | Used for treating nausea, vomating, gastrointestinal disorders and centarl nervous system | WALTON S.A. (ES) | 1991-06-25 | — | — | US | disclosed |