Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.54 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837365 | 0.87 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11281418 | 0.86 | LMNA (0.54) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6481160 | 0.84 | BAZ2B (0.47) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6479967 | 0.84 | BAZ2B (0.47) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9836660 | 0.80 | ALDH1A1 (0.55) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6050604 | 0.76 | BAZ2B (0.47) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6050613 | 0.74 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11402926 | 0.72 | KMT2A (0.56) | BAZ2BBAZ2AALDH1A1KDM4EPOLB | |
| SCHEMBL29576801 | 0.72 | KMT2A (0.56) | BAZ2BBAZ2AALDH1A1KDM4EPOLB | |
| SCHEMBL10084828 | 0.72 | LMNA (0.58) | BAZ2BBAZ2AALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269295-B1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1991-06-26 | — | — | EP | disclosed |
| US-4877793-A | CARDIOVASCULAR DISORDERS | THE BOOTS COMPANY, PLC (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0269295-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1988-06-01 | — | — | EP | disclosed |