Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837023 | 0.83 | MAPT (0.58) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL9863084 | 0.83 | MAPK1 (0.45) | MAPTALDH1A1MAPK1LMNAHTT | |
| SCHEMBL6351039 | 0.83 | MAPT (0.59) | MAPTMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL2335559 | 0.79 | MAPT (0.40) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL2335563 | 0.79 | MAPT (0.40) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL29367971 | 0.78 | AHR (0.46) | MAPTMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL2335555 | 0.77 | GAA (0.51) | MAPTALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL5992360 | 0.76 | VCAM1 (0.60) | MAPTMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL5611161 | 0.75 | NOTUM (0.44) | MAPTMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL17320639 | 0.74 | GPR35 (0.45) | MAPTMEN1ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261478-B1 | 4,5-DIHYDRO-OXAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1991-04-24 | — | — | EP | disclosed |
| US-4818760-A | ANTIULCER AGENT, ENZYME INHIBITOR | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1989-04-04 | — | — | US | disclosed |
| EP-0261478-A1 | 4,5-Dihydro-oxazole derivatives, process for their preparation and their use | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1988-03-30 | — | — | EP | disclosed |