Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837130 | 0.98 | PTPN1 (0.52) | NPC1RAB9APTPN1ALDH1A1BLM | |
| SCHEMBL11216066 | 0.81 | MEN1 (0.62) | NPC1RAB9APTPN1ALDH1A1KDM4E | |
| SCHEMBL15973607 | 0.80 | MAPT (0.58) | NPC1RAB9APTPN1ALDH1A1CA1 | |
| SCHEMBL10187752 | 0.80 | GSK3B (0.55) | NPC1RAB9AALDH1A1POLBGAA | |
| SCHEMBL7436867 | 0.80 | HSD17B3 (0.52) | NPC1RAB9APTPN1ALDH1A1BLM | |
| SCHEMBL14830961 | 0.80 | ERCC5 (0.58) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| Methane SCHEMBL9836231 | 0.79 | ESR1 (0.54) | NPC1RAB9APTPN1ALDH1A1TDP1 | |
| SCHEMBL7439603 | 0.77 | RAB9A (0.47) | NPC1RAB9APTPN1ALDH1A1BLM | |
| SCHEMBL7443170 | 0.77 | ESR1 (0.56) | NPC1RAB9APTPN1ALDH1A1TDP1 | |
| SCHEMBL2330432 | 0.76 | CYP1A2 (0.60) | RAB9AALDH1A1KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238357-B1 | 1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-29 | — | — | EP | disclosed |