Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837057 | 0.85 | SRD5A1 (0.47) | SRD5A1MAOAEGFRIKBKBKDM5A | |
| SCHEMBL9834724 | 0.82 | PTGS2 (0.61) | SRD5A1MAOAIKBKBKDM5APTGS2 | |
| SCHEMBL9837623 | 0.79 | MAOA (0.54) | MAOAEGFRTTRKDM5APTGS2 | |
| SCHEMBL9834639 | 0.78 | IKBKB (0.61) | SRD5A1MAOAEGFRTTRIKBKB | |
| SCHEMBL9836830 | 0.76 | TTR (0.44) | SRD5A1MAOAEGFRTTRIKBKB | |
| SCHEMBL9834774 | 0.71 | TTR (0.49) | MAOATTRIKBKBKDM5APTGS2 | |
| SCHEMBL5236219 | 0.70 | MAOA (0.64) | SRD5A1MAOAEGFRIKBKBATP1A1 | |
| SCHEMBL9837104 | 0.70 | IKBKB (0.63) | MAOATTRIKBKBKDM5APTGS2 | |
| SCHEMBL5274928 | 0.69 | TSHR (0.45) | SRD5A1 | |
| SCHEMBL4333679 | 0.69 | SRD5A1 (0.61) | SRD5A1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |