Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835495 | 0.89 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAANPC1 | |
| SCHEMBL9835624 | 0.89 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAANPC1DAO | |
| SCHEMBL9836386 | 0.84 | TBXAS1 (0.72) | TBXAS1ALDH1A1GAACYP2B6 | |
| SCHEMBL9834927 | 0.81 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAANPC1CYP2B6 | |
| SCHEMBL9837178 | 0.79 | TBXAS1 (0.65) | TBXAS1ALDH1A1GAANPC1 | |
| Nafagrel SCHEMBL6570453 | 0.76 | TBXAS1 (0.61) | TBXAS1CYP2B6 | |
| Hydrochloric Acid SCHEMBL10823706 | 0.75 | TBXAS1 (0.60) | TBXAS1CYP2B6 | |
| Nafagrel SCHEMBL7301697 | 0.75 | TBXAS1 (0.60) | TBXAS1CYP2B6 | |
| SCHEMBL3347584 | 0.75 | TBXAS1 (0.59) | TBXAS1ALDH1A1NPC1DAO | |
| Nafagrel SCHEMBL7274167 | 0.74 | TBXAS1 (0.59) | TBXAS1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | claimed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | claimed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | claimed |