Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835495 | 0.90 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAANPC1RAB9A | |
| SCHEMBL9835624 | 0.90 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAANPC1 | |
| SCHEMBL9834927 | 0.82 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAANPC1RAB9A | |
| SCHEMBL9836178 | 0.79 | TBXAS1 (1.00) | TBXAS1ALDH1A1GAANPC1 | |
| SCHEMBL9870926 | 0.74 | RAB9A (0.43) | TBXAS1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9836834 | 0.71 | ALDH1A1 (0.44) | TBXAS1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9836336 | 0.70 | TBXAS1 (0.78) | TBXAS1ALDH1A1GAANPC1 | |
| SCHEMBL9836386 | 0.70 | TBXAS1 (0.72) | TBXAS1ALDH1A1GAA | |
| SCHEMBL9836683 | 0.69 | TBXAS1 (0.52) | TBXAS1ALDH1A1GAANPC1RAB9A | |
| SCHEMBL9834618 | 0.69 | TBXAS1 (0.52) | TBXAS1ALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |